345. Hematopoietic Stem-Progenitor Cells Express CD52 mRNA and Membrane Protein

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Hematopoietic Stem and Progenitor Cells

Mature blood cells have a finite life-span and must be continuously replaced throughout life. Blood cells are produced by the proliferation and differentiation of a very small population of pluripotent hematopoietic stem cells (HSCs) that also have the ability to replenish themselves by self-renewal (Figure 1). During differentiation, the progeny of HSCs progress through various intermediate ma...

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 Background and purpose: Human pluripotent stem cells (hPSCs) with the ability to differentiate into adult cells have provided a new perspective for treatment of some diseases. But, the efficiency of differentiation methods to generate hematopoietic progenitor cells (HPCs) is faced with multiple challenges. In the present study, we investigated the formation of hemato-endothelial-like structure...

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IN NORTH AMERICA TOLL-FREE T. 1 800 667 0322 TOLL-FREE F. 1 800 567 2899 T. +1 604 877 0713 F. +1 604 877 0704 E. [email protected] IN EUROPE TOLL-FREE T. 00 800 7836 2355 TOLL-FREE F. 00 800 7836 2300 T. +33 (0)4 76 04 75 30 F. +33 (0)4 76 18 99 63 E. [email protected] IN AUSTRALIA TOLL-FREE T. 1 800 060 350 F. +61 (03) 9338 4320 E. [email protected] IN SINGAPORE T. +(65) 6776 7754 F. +...

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ژورنال

عنوان ژورنال: Molecular Therapy

سال: 2006

ISSN: 1525-0016

DOI: 10.1016/j.ymthe.2006.08.403